Oncoptysis as the primary presentation of metastatic melanoma: A case report.

Am J Emerg MedJun 17, 2026 (epub)

Nini Phan, Anthony Hackett, Robert E Schmitt

✦ AI-curated · Sources linked

Case in brief

An 88-year-old female presented to the emergency department with cough and hemoptysis. She expectorated abnormal tissue, initially thought to be lung tissue. Imaging revealed an 8 × 7 cm mass in the right lower lobe, confirmed as metastatic malignant melanoma. After managing her respiratory distress, she opted for hospice care instead of aggressive chemotherapy.

What made this case unusual

This case is notable for the presentation of oncoptysis, where the patient expectorated tumor tissue, a rare occurrence in metastatic melanoma.

Diagnostic / clinical pearl

Clinicians should consider malignancy in the differential diagnosis of hemoptysis, especially in patients with a history of melanoma and atypical sputum.

Why it matters

This case emphasizes the need for careful diagnostic evaluation in unusual presentations of malignancy, which can inform palliative care decisions.

Source

Published in Am J Emerg Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

ShareTelegramLinkedIn

AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

More in Oncology (Medical)

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text

Prefer listening? Personalized audio digests are available with Pro.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.