Collaborative care intervention for risky opioid use among primary care patients: The STOP randomized clinical trial.

AddictionJun 22, 2026 (epub)

Jennifer McNeely, Geetha A Subramaniam, Rebecca Stone et al.

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In 30 seconds

The STOP randomized controlled trial evaluated a collaborative care intervention aimed at reducing risky opioid use among primary care patients. Conducted across five U.S. sites, the study involved 202 patients with current risky opioid use. Results showed that while the intervention did not significantly reduce mean days of risky opioid use compared to enhanced usual care, fewer participants in the STOP group progressed to moderate-severe opioid use disorder at 6 months.

Key findings

  • Mean days of risky opioid use at 180 days were 12.2 in STOP vs 15.5 in EUC.
  • Only 1.1% of STOP participants developed moderate-severe OUD at 6 months compared to 11.4% in EUC.
  • At 12 months, 3.4% of STOP participants had moderate-severe OUD vs 5.3% in EUC.

Why it matters

This study highlights the challenges in reducing risky opioid use in primary care settings, particularly among patients with significant pain and comorbidities. Understanding the effectiveness of collaborative care interventions can inform future strategies to address opioid misuse.

Source

Published in Addiction. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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