Congenital dengue with detection of viral RNA in cerebrospinal fluid: A case report.
Felipe Cabezón Jarvis, Valentina Medrano Paz, Mariana Rodríguez Braumüller
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Case in brief
A 35-week preterm newborn presented with fever and hyporesponsiveness on day seven of life, following maternal dengue infection. Diagnostic testing revealed dengue virus RNA in both serum and cerebrospinal fluid. The infant exhibited thrombocytopenia and coagulation abnormalities but had normal neurological findings and a favorable clinical outcome, emphasizing the need to consider congenital dengue in similar clinical scenarios.
Diagnostic / clinical pearl
Congenital dengue should be considered in cases of neonatal sepsis, particularly when there is a history of maternal dengue infection close to delivery.