Prognostic value of albuminuria in heart failure with preserved ejection fraction: A systematic review.
Leandro Barbagelata, Walter Masson, Santiago Decotto et al.
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In 30 seconds
This systematic review evaluated the prognostic significance of albuminuria in adults with heart failure with preserved ejection fraction (HFpEF). The analysis included 14 studies and found that albuminuria was consistently linked to increased risks of mortality, heart failure hospitalization, and adverse cardiovascular outcomes, independent of renal function.
Key findings
- Albuminuria was associated with higher risks of mortality and heart failure hospitalization.
- The prognostic value of albuminuria was independent of renal function.
- Several studies linked albuminuria to myocardial remodeling and cardiorenal dysfunction.
Why it matters
Understanding the prognostic implications of albuminuria in HFpEF can enhance risk stratification and help identify patients at higher risk for adverse outcomes, potentially guiding clinical management.