Benzalkonium Chloride in Eye Drops Causing Allergic Contact Dermatitis: A Case Series.

Australas J DermatolJul 2, 2026 (epub)
Case ReportDermatologyOphthalmologyAllergy & Immunology

Arav Kannen, Penelope Harrison, Elizabeth Christou

✦ AI-curated · Sources linked

Case in brief

The report describes three patients who developed allergic contact dermatitis (ACD) associated with benzalkonium chloride (BAK) in ophthalmic drops. BAK is a commonly used preservative in eye-drop formulations. The abstract identifies the suspected allergen and clinical presentation but does not provide patient-level findings, diagnostic testing, management, or outcomes.

What made this case unusual

The report focuses on BAK allergy from eye drops in patients with atopic dermatitis and in those using dupilumab; the abstract does not specify the individual cases or their outcomes.

Diagnostic / clinical pearl

Consider BAK in ophthalmic drops as a potential contact allergen when assessing ACD associated with eye-drop use.

Source

PubMed · PMID 42389932

Published in Australas J Dermatol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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