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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedClinical ResearchInfectious Diseases

Serum Virus-Neutralizing Antibody Titers in Clinical Trial Participants With and Without Immunocompromise Receiving Pemivibart, a Long-Acting Monoclonal Antibody for COVID-19.

J Infect DisOct 15, 2026

This analysis of phase 3 CANOPY and phase 1 trial data examined measured and calculated serum virus-neutralizing antibody titers after pemivibart in participants with and without significant immunocompromise.

Why it matters

Neutralization against circulating SARS-CoV-2 variants may differ substantially from responses to earlier variants, so prior immune experience does not necessarily imply strong cross-protection.

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Also worth knowing

Clinical ResearchDermatology

Efficacy and safety of subcutaneous efgartigimod with prednisone in moderate-to-severe pemphigus (ADDRESS): a global, phase III, randomised controlled, double-blind trial.

ADDRESS was a global, phase III, multicentre, randomised, double-blind, placebo-controlled trial of adults with newly diagnosed or relapsing moderate-to-severe pemphigus.

Br J DermatolOct 19, 2026Read summary
Clinical ResearchPediatricsOpen access

Paediatric Helicobacter pylori infection and allergic and inflammatory diseases: a contemporary systematic review with meta-analysis.

This systematic review and meta-analysis assessed recent evidence on Helicobacter pylori infection and allergic or immune-mediated diseases in children.

Eur J PediatrOct 19, 2026Read summary
Clinical ResearchOrthopedic Surgery

Metal Hypersensitivity Reactions Following Spinal Implants: A Systematic Review.

This systematic review examined clinical presentation, diagnostic approaches, and outcomes of metal hypersensitivity after spinal implant surgery in adults.

JBJS RevOct 19, 2026Read summary
Case ReportEndocrinology

Approach to the patient with APS-1/APECED.

This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.

J Clin Endocrinol MetabOct 16, 2026Read case
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