Intravascular imaging guidance for percutaneous coronary intervention and clinical outcomes: meta-analyses of randomized controlled trials.
Cardiovasc Interv TherJul 4, 2026 (epub)
Yuriko Hiruma, Tetsuya Saito, Mariko Sugii et al.
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In 30 seconds
This network meta-analysis of 29 randomized controlled trials involving 23,338 patients assessed the long-term outcomes of intravascular imaging-guided percutaneous coronary intervention (PCI). The study found that imaging-guided PCI significantly reduced the risk of major adverse cardiac events (MACE) compared to angiography-guided PCI, with a hazard ratio of 0.74 (95% CI, 0.63-0.87).
Key findings
- Imaging-guided PCI reduced MACE risk compared to angiography-guided PCI (HR, 0.74; 95% CI, 0.63-0.87).
- No significant difference in MACE risk was found between IVUS- and OCT-guided PCI.
- The benefit of imaging guidance was more pronounced in patients with complex lesions and those from Asian populations.
Why it matters
Understanding the benefits of intravascular imaging in PCI can help clinicians optimize treatment strategies, particularly for patients with complex lesions or those from specific demographic groups, potentially improving patient outcomes.