Prevalence of neurocysticercosis among individuals with seizure presentations in South East Asia: A systematic review and meta- analysis.
Popular Pokhrel, Nitesh Neupane, Gopal Pokhrel et al.
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In 30 seconds
This systematic review and meta-analysis estimated the prevalence of neurocysticercosis (NCC) among individuals with seizure presentations in South-East Asia. Analyzing 50 studies with 10,743 individuals, the pooled prevalence of NCC was found to be 22% (95% CI: 19%-25%). Community-based studies showed a higher prevalence of 30% compared to 20% in hospital-based studies.
Key findings
- The pooled prevalence of NCC among individuals with seizures in SEA was 22% (95% CI: 19%-25%).
- Community-based studies reported a higher prevalence of 30% (95% CI: 22%-38%).
- The highest country-wise prevalence was in India at 24% (95% CI: 19%-28%).
- Substantial heterogeneity was observed across studies (I² > 90%).
Why it matters
Understanding the prevalence of neurocysticercosis in individuals with seizures is crucial for clinicians in endemic regions, as it informs diagnosis and management strategies for epilepsy and related conditions.
What to keep in mind
Substantial heterogeneity across studies and the presence of publication bias were noted.