The association of dietary inflammation index (DII) and health-related outcomes: An umbrella review of systematic reviews.

Clin Nutr ESPENJul 11, 2026 (epub)

Vasiliki Gkesou, Xenophon Theodoridis, Androniki Papaemmanouil et al.

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In 30 seconds

This umbrella review examined the association between the dietary inflammatory index (DII) and various health outcomes, analyzing 90 systematic reviews and meta-analyses. It found that higher DII scores, indicating pro-inflammatory diets, are linked to adverse health effects compared to lower scores. The overall evidence quality was low or critically low.

Key findings

  • High DII scores are associated with adverse health outcomes across multiple domains, including cancer and cardiovascular diseases.
  • A total of 90 systematic reviews and meta-analyses were included in the analysis.
  • Most included reviews were rated as having low or critically low methodological quality.

Why it matters

Understanding the impact of dietary inflammation on health outcomes can guide clinicians in advising patients on dietary choices that may reduce health risks. Promoting anti-inflammatory diets could be a preventive strategy against various diseases.

What to keep in mind

The overall certainty of evidence is limited due to the low methodological quality of most included reviews.

Source

Published in Clin Nutr ESPEN. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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