A systematic review of Nipah virus disease epidemiological parameters, outbreaks, and mathematical models.

In 30 seconds

This systematic review examined the epidemiology, outbreaks, and mathematical models of Nipah virus disease, focusing on data from south and southeast Asia. The review included 243 parameters and 23 outbreaks from 119 studies. The pooled case-fatality ratio varied significantly, with estimates from 9.1% in Singapore to 81.9% in Bangladesh.

Key findings

• IgG seroprevalence in the general population ranged from 0% to 12.5%.
• Pooled case-fatality ratio estimates ranged from 9.1% to 81.9%.
• The median incubation period was estimated at 8.77 days.
• Only eight out of 39 mathematical models were fitted to data.

Why it matters

Understanding the epidemiological parameters and risks associated with Nipah virus is crucial for public health planning and response, especially in regions where outbreaks occur. This knowledge can inform prevention strategies and resource allocation.