A systematic review and meta-analysis of the economic burden of carbapenem-resistant Enterobacterales (CRE) infection.
Int J Infect DisJul 14, 2026 (epub)
Clinical ResearchInfectious Diseases
Jiangnianyong Shen, Jiabin Lin, Xian Zhu et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the economic burden of carbapenem-resistant Enterobacterales (CRE) infections, focusing on hospitalization costs, length of stay (LOS), and mortality. The analysis included 21 studies and found that CRE infections led to a mean difference in LOS of 14.16 days and an odds ratio for mortality of 1.96 compared to carbapenem-susceptible infections.
Key findings
- CRE infection resulted in increased hospitalization costs compared to control groups.
- Mean difference in length of stay for CRE infection was 14.16 days.
- CRE infection was associated with higher mortality, with an odds ratio of 1.96.
Why it matters
Understanding the economic burden of CRE infections is crucial for healthcare systems, as it highlights the need for effective prevention and control strategies to mitigate both clinical and financial impacts.