The impact of HIV coinfection on mpox patients: a systematic review and meta-analysis.
Emerg Microbes InfectJul 27, 2026 (epub)
Lei Ji, Defu Yuan, Fuchun Wang et al.
✦ AI-curated · Sources linked
In 30 seconds
This systematic review and meta-analysis examined the impact of HIV coinfection on clinical outcomes in mpox patients, analyzing data from 29 studies involving 15,522 patients. The study found that HIV coinfection was associated with a 50% increase in hospitalization (RR = 1.50) and a 354% increase in mortality (RR = 4.54), indicating greater clinical severity in this population.
Key findings
- HIV coinfection was linked to a 50% increase in hospitalization (RR = 1.50).
- Mortality rates were 354% higher in HIV coinfected patients (RR = 4.54).
- Coinfected patients exhibited higher rates of syphilis, HBV, and HCV coinfections.
- Lower levels of albumin, calcium, and hemoglobin were observed in HIV coinfected individuals.
Why it matters
Understanding the impact of HIV coinfection on mpox patients is crucial for clinicians, as it highlights the need for enhanced monitoring and tailored management strategies to improve patient outcomes in this vulnerable population.