Cardiovascular risks in psychiatric disorders and psychiatric risks in cardiovascular disorders: implications for prevention and clinical management - a large-scale umbrella review encompassing 76 meta-analyses.
Michele Fornaro, Chiara Di Lorenzo, Augusto Esposito et al.
✦ AI-curated · Sources linked
In 30 seconds
This umbrella review analyzed 76 meta-analyses to explore the co-occurrence of psychiatric and cardiovascular disorders. It found that 91.7% of prevalence estimates met moderate to strong credibility criteria. Notably, major depressive disorder was associated with a 41.9% prevalence in heart failure patients. The study emphasizes the importance of integrated care for these comorbid conditions.
Key findings
- Major depressive disorder prevalence in heart failure was 41.9% (95% C.I. = 36.7-47.1%).
- Orthostatic hypotension prevalence in Lewy body dementia was 58% (95% C.I. = 50-66%).
- Anxiety prevalence in atrial fibrillation patients undergoing pulmonary vein isolation was 25.0% (95% C.I. = 12.0-46.0%).
- Clozapine-associated cardiomyopathy had an absolute death rate of 0.0003 (95% C.I. = 0.0001-0.0012).
Why it matters
Understanding the prevalence and interrelation of psychiatric and cardiovascular disorders is crucial for clinicians. This knowledge can inform more effective, multidisciplinary management strategies, ultimately improving patient outcomes in those with multimorbidity.