Lifestyle modifications in individuals with blood pressure beyond treatment target despite pharmacological treatment: design and baseline characteristics of the MeDiPA randomised controlled trial.
Blood PressAug 6, 2026 (epub)
Ana R S de Sousa, Tor Ole Klemsdal, Reza Ghiasvand et al.
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In 30 seconds
The MeDiPA randomized controlled trial investigates the effects of lifestyle modifications on blood pressure in patients with uncontrolled hypertension despite pharmacological treatment. The study included 66 participants with a mean age of 59 years, all taking at least two antihypertensives. The primary outcome is changes in 24-hour ambulatory blood pressure after 6 months.
Key findings
- Participants had a mean blood pressure of 137/90 mmHg at baseline.
- 66 participants were included, with 56% being women.
- 85% of participants were Norwegian and 83% had higher education.
- Mean BMI was 32.0 kg/m², indicating overweight or obesity.
Why it matters
Understanding the impact of lifestyle modifications on blood pressure in patients already on antihypertensive medication is crucial for improving treatment strategies and achieving recommended blood pressure targets.