Global, regional, and national prevalence of peripheral arterial disease in 2023: an updated systematic review and modelling study.

Lancet Glob HealthJul 21, 2026 (epub)
Clinical ResearchCardiologyGeriatrics

Jiali Zhou, Xinyu Liu, Shiyi Shan et al.

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In 30 seconds

This systematic review and modelling study estimated the global prevalence of peripheral arterial disease (PAD) in 2023, analyzing data from over 9.7 million participants across 37 countries. The global prevalence among individuals aged 25 years and older was found to be 6.58%, equating to approximately 316.54 million affected individuals. The study highlights significant age and sex-related variations in PAD prevalence.

Key findings

  • Global prevalence of PAD in 2023 was 6.58%, affecting approximately 316.54 million individuals.
  • Prevalence increased with age, from 4.31% in ages 25-29 to 22.09% in ages 90-99.
  • Women had a slightly higher prevalence (6.79%) compared to men (6.37%).
  • Current smoking was associated with a higher odds ratio of 2.85 for PAD.

Why it matters

Understanding the prevalence and associated factors of peripheral arterial disease is crucial for clinicians to identify at-risk populations and implement early detection strategies. This knowledge can inform public health initiatives aimed at reducing the burden of PAD, particularly in low- and middle-income countries.

Source

Published in Lancet Glob Health. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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