Bradycardia, rare extreme QT prolongation and Giant inverted T waves following Grayanotoxin (mad honey) intoxication: A short communication and literature review.
Ertan Aydın, Devrim Kurt, Gökhan Gök
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Case in brief
A 62-year-old male with no prior cardiac history presented with dizziness, nausea, and cold sweats after ingesting mad honey. He was found to have sinus bradycardia, hypotension, and marked QTc prolongation with giant inverted T waves on ECG. After treatment with intravenous hydration and magnesium sulfate, he experienced rapid recovery within 24 hours.
What made this case unusual
The case highlights extreme QT prolongation and giant inverted T waves as rare manifestations of mad honey intoxication, which are not commonly associated with this condition.
Diagnostic / clinical pearl
Clinicians should consider mad honey intoxication in patients with unexplained bradycardia and hypotension, particularly in endemic areas, due to its potential for severe cardiac complications.
Why it matters
This case emphasizes the need for vigilant cardiac monitoring and electrolyte management in patients with mad honey poisoning to prevent life-threatening arrhythmias.