Transcatheter Mitral Valve Replacement in Valve-in-Valve, Valve-in-ring, and Valve-in-Mitral Annular Calcification: A Case-based Review.

Am J CardiolJul 25, 2026 (epub)

Antonella Millin, Ioannis Skalidis, Lorenzo Fargione et al.

✦ AI-curated · Sources linked

Case in brief

This case-based review discusses transcatheter mitral valve replacement (TMVR) in patients with failed mitral bioprostheses, annuloplasty rings, and mitral annular calcification. It highlights three cases that illustrate the complexities of preprocedural planning and postprocedural management. While valve-in-valve procedures show predictable outcomes, valve-in-ring and valve-in-mitral annular calcification procedures present significant challenges due to anatomical intricacies and higher procedural risks.

Diagnostic / clinical pearl

Clinicians should recognize that valve-in-ring and valve-in-mitral annular calcification procedures carry higher risks, necessitating careful preprocedural planning and patient selection.

Why it matters

Advancements in imaging and device design are crucial for improving outcomes in high-risk patients undergoing TMVR, particularly in complex anatomical scenarios.

Source

Published in Am J Cardiol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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