Conventional and nonconventional therapies for pesticide-induced cardiotoxicity: A systematic review.
Douglas Lamounier de Almeida, Sarah Júnia Gomes da Costa, Verônica Cecília Silva et al.
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In 30 seconds
This systematic review synthesized evidence on cardioprotective strategies against pesticide-induced cardiotoxicity, focusing on both conventional and natural product-based therapies. A total of 85 studies were included, primarily involving in vivo models. The review found that various natural compounds, such as vitamin E and resveratrol, showed protective effects, improving cardiovascular outcomes.
Key findings
- Natural compounds like vitamin E and resveratrol demonstrated protective effects against pesticide-induced cardiotoxicity.
- Interventions improved hemodynamic and electrocardiographic parameters in the studied models.
- Most studies focused on natural products rather than conventional antidotes for cardioprotection.
Why it matters
Understanding the potential cardioprotective effects of various interventions against pesticide exposure is crucial for developing strategies to mitigate environmental health risks. This knowledge can inform future research and therapeutic approaches in cardiotoxicity management.