Potential Role of Omega-3 Supplementation in Modulating Symptoms and Holter Parameters in Pediatric Inappropriate Sinus Tachycardia.
Mohamed Ahmed El-Baz, Somaia Abdel Samie El Wan, Rodina Sobhy Mohamed et al.
✦ AI-curated · Sources linked
In 30 seconds
This randomized controlled trial evaluated the impact of omega-3 supplementation on heart rate and heart rate variability in 60 children aged 12-16 with inappropriate sinus tachycardia. After 3 months, the omega-3 group demonstrated significant reductions in maximum heart rate (from 160.5 to 142.2 bpm) and average heart rate (from 98.9 to 90.7 bpm), alongside improved heart rate variability indices.
Key findings
- Maximum heart rate decreased from 160.5 ± 17.9 to 142.2 ± 15.7 bpm in the omega-3 group.
- Average heart rate reduced from 98.9 ± 4.7 to 90.7 ± 5.5 bpm after omega-3 supplementation.
- 63.3% of the omega-3 group showed marked clinical improvement compared to controls.
- Obesity and pre-hypertension were linked to poorer responses to omega-3 therapy.
Why it matters
The findings suggest that omega-3 supplementation may be an effective strategy for managing inappropriate sinus tachycardia in pediatric patients, potentially improving heart rate control and variability. Understanding the factors that influence treatment response is crucial for optimizing care.