In Vitro comparison of herbal and conventional antifungals against Candida strains in Oral candidiasis: A systematic review and meta-analysis.
Nurdiana, Supawadee Naorungroj, Kraisorn Sappayatosok et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the in vitro antifungal activity of herbal versus conventional antifungals against various Candida strains. The analysis included 25 studies and found that certain herbal antifungals were equally or more effective than conventional options against Candida dubliniensis, Candida lusitaniae, and Candida tropicalis, while conventional antifungals were superior against Candida krusei and Candida parapsilosis.
Key findings
- Certain herbal antifungals showed equal or greater efficacy than conventional antifungals against Candida dubliniensis, Candida lusitaniae, and Candida tropicalis.
- Piper betle L. exhibited significant inhibitory potential against Candida strains.
- Conventional antifungals outperformed herbal antifungals against Candida krusei and Candida parapsilosis.
Why it matters
The findings suggest that herbal antifungals may offer alternative treatment options for oral candidiasis, particularly in light of increasing resistance to conventional antifungal therapies. Understanding these alternatives is crucial for effective patient management.