Oropharyngeal lymphogranuloma venereum caused by Chlamydia trachomatis genovariant L2b in men who have sex with men in Taiwan.
Pin-Cheng Chu, Nan-Yao Lee, Ming-Chi Li et al.
✦ AI-curated · Sources linked
Case in brief
Two men who have sex with men (MSM) living with HIV in Taiwan were diagnosed with oropharyngeal lymphogranuloma venereum (LGV) caused by Chlamydia trachomatis genovariant L2b. The first case was asymptomatic, identified through routine screening due to elevated RPR titers, while the second presented with oral ulcers and anorectal symptoms. Both cases were treated successfully with doxycycline, achieving microbiological cure.
What made this case unusual
The first case was asymptomatic, highlighting that oropharyngeal LGV can present without typical symptoms, while the second case mimicked aphthous stomatitis.
Diagnostic / clinical pearl
Clinicians should consider oropharyngeal LGV in MSM, even in the absence of anorectal symptoms, and utilize multi-site testing for Chlamydia trachomatis.
Why it matters
This case emphasizes the need for awareness of atypical presentations of STIs, particularly in populations at risk, to ensure timely diagnosis and treatment.