Photodynamic therapy as a key adjunct in the multimodal management of cutaneous Fusarium solani infection in an immunocompromised patient: A case report.
Photodiagnosis Photodyn TherAug 4, 2026 (epub)
Yiping Liang, Yahui Feng, Huiyu Zhang et al.
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Case in brief
A 60-year-old male with myelofibrosis on ruxolitinib presented with progressive cutaneous granulomas on his left thumb and back. Diagnosis of cutaneous fusariosis was confirmed through clinical and laboratory methods. Initial treatment with itraconazole and photodynamic therapy (PDT) led to significant improvement, despite later findings of itraconazole resistance. The regimen was adjusted to terbinafine and PDT, resulting in complete remission at six months.
Diagnostic / clinical pearl
Clinicians should consider a multimodal approach, including systemic antifungal therapy and photodynamic therapy, for managing refractory cutaneous Fusarium solani infections in immunocompromised patients.