Left ventricular hypertrophy in hypertension: a systematic review and meta-analysis of echocardiographic studies published from 2011 to 2025.
Elisa Gherbesi, Andrea Faggiano, Carla Sala et al.
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In 30 seconds
This systematic review and meta-analysis examined the prevalence of left ventricular hypertrophy (LVH) in 74,632 hypertensive patients from studies published between 2011 and 2025. The analysis found an overall LVH prevalence of 36.6% (95% CI: 33.4-40%). It highlighted significant gender differences, with men having a lower probability of LVH compared to women (OR=0.62, CI: 0.48-0.80, P<0.0001).
Key findings
- The overall prevalence of LVH in hypertensive patients was 36.6% (95% CI: 33.4-40%).
- Men had a lower probability of LVH compared to women (OR=0.62, CI: 0.48-0.80, P<0.0001).
- The risk of concentric LVH was almost twice as high as eccentric LVH (OR=1.94, CI: 1.52-2.49, P<0.0001).
Why it matters
The high prevalence of LVH indicates ongoing challenges in managing hypertension and preventing hypertensive heart disease. Understanding these patterns can guide clinicians in tailoring treatment strategies, particularly for at-risk populations such as women.