Interventions to improve viral suppression and adherence to antiretroviral therapy among people living with HIV: a systematic review and network meta-analysis.
Steve Kanters, David S Lawrence, Vanessa S McLennan et al.
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In 30 seconds
This systematic review and network meta-analysis evaluated adherence interventions for antiretroviral therapy among people living with HIV in low- and middle-income countries. The study found that reminders and supporter interventions significantly improved adherence at 24 weeks, with odds ratios of 1.53 and 1.82, respectively. Overall, tailored interventions could enhance treatment outcomes and support epidemic control efforts.
Key findings
- Reminders improved adherence at 24 weeks with an odds ratio of 1.53 and a risk difference of 9.4%.
- Supporters also enhanced adherence at 24 weeks with an odds ratio of 1.82 and a risk difference of 12.8%.
- Counselling showed improved adherence at 12 weeks with an odds ratio of 2.53 and a risk difference of 18.8%.
- Supporters improved viral suppression at 48 weeks with an odds ratio of 1.34 and a risk difference of 6.5%.
Why it matters
Improving adherence to antiretroviral therapy is crucial for achieving viral suppression and reducing HIV transmission. Effective interventions can enhance treatment outcomes, particularly in resource-limited settings, contributing to global health goals.