Diagnostic yield of 8G versus 11G transpedicular vertebral biopsy needles in suspected tuberculous spondylitis: a prospective randomized controlled study.
Clin RadiolJul 17, 2026 (epub)
S Pandey, P Aggarwal, D N Srivastava et al.
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In 30 seconds
This randomized controlled trial compared the diagnostic yield of 8G versus 11G transpedicular biopsy needles in 50 patients suspected of tuberculous spondylitis. The study found no significant difference in diagnostic yield or complications between the two needle sizes, with 32% of 8G samples and 24% of 11G samples testing positive via microbiological methods.
Key findings
- At least one microbiological test was positive in 32% of the 8G group and 24% of the 11G group (p>0.05).
- Histopathology suggested tuberculosis in 40% of the 8G group and 36% of the 11G group (p=0.88).
- Diagnostic samples were obtained in 13 patients from the 8G group and 12 from the 11G group (p=0.62).
Why it matters
Understanding the diagnostic yield of different biopsy needle sizes can help clinicians make informed decisions regarding the most effective approach for diagnosing tuberculous spondylitis, potentially impacting patient management and outcomes.