Acceptability and Effectiveness of Point-of-Care HCV Testing in Low- and Middle-Income Countries: A Systematic Review.
Liver IntSep 1, 2026
Win Lei Yee, Thin Mar Win, Bridget Draper et al.
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In 30 seconds
This systematic review evaluated the effectiveness and acceptability of Point-of-Care (POC) HCV testing in low- and middle-income countries (LMICs). Out of 2018 reports screened, 20 met the criteria for data extraction, revealing that in 11 studies with onsite services, testing and treatment uptake exceeded 90%. The findings support the potential for decentralized testing to enhance HCV care.
Key findings
- In 11 reports with onsite services, testing and treatment uptake exceeded 90%.
- HCV self-testing among high-risk populations showed high acceptability rates of 91%-99%.
- Oral-based self-testing had higher recommendation rates (94%-99%) compared to blood-based testing (86.1%).
Why it matters
Decentralized Point-of-Care testing for HCV can significantly improve diagnosis and treatment rates in LMICs, addressing barriers posed by centralized laboratory services. This approach may enhance overall public health outcomes in these regions.