Favorable clinical and microbiological outcomes of a war-associated prosthetic joint infection caused by Klebsiella pneumoniae treated with combined phage-colistin therapy.

Int J Infect DisAug 25, 2026 (epub)
Case ReportInfectious DiseasesOrthopedic Surgery

Lucas Mora-Quilis, Mireia Bernabéu-Gimeno, Marco Pardo-Freire et al.

✦ AI-curated · Sources linked

Case in brief

A patient with a prosthetic elbow infection due to multidrug-resistant Klebsiella pneumoniae, following a war-related injury, presented after failing multiple antibiotic treatments. The infection was successfully managed with a combination of personalized phage therapy and colistin, resulting in significant clinical improvement and microbiological clearance, with no signs of persistent infection at follow-up.

Diagnostic / clinical pearl

This case underscores the potential of personalized phage therapy as an effective adjunctive treatment for complex prosthetic joint infections caused by multidrug-resistant organisms when conventional antibiotics are ineffective.

Source

PubMed · PMID 42641938

Published in Int J Infect Dis. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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