Prevalence of methicillin-resistant Staphylococcus aureus in Iran: A systematic review and meta-analysis.
Fahad Rajab Alfahdawi, Negar Narimisa, Roghayeh Mohammadzadeh et al.
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In 30 seconds
This systematic review and meta-analysis assessed the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in Iran, analyzing data from 89 studies. The pooled prevalence of MRSA among human S. aureus isolates was found to be 46.4% (95% CI: 43.6-49.3%). The study highlights significant heterogeneity among the included studies.
Key findings
- The pooled prevalence of MRSA was 46.4% among human S. aureus isolates.
- Publication bias was indicated, with a reduced pooled estimate of 38.8% after trim-and-fill analysis.
- Type III SCCmec was the most prevalent at 44%, while type IVb was the least at 6%.
Why it matters
Understanding the prevalence of MRSA is crucial for healthcare providers to implement effective infection control measures and antimicrobial stewardship, particularly in high-risk settings.
What to keep in mind
The study noted considerable heterogeneity among the included studies, which may affect the reliability of the pooled estimates.