Global Epidemiology of Diabetic Foot: A Systematic Review and Meta-Analysis.
Massimo Carollo, Ylenia Ingrasciotta, Salvatore Crisafulli et al.
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In 30 seconds
This systematic review and meta-analysis examined the global epidemiology of diabetic foot (DF) disease in adults with diabetes mellitus, analyzing 89 studies. The findings revealed a pooled incidence of 10.93 cases/1000 person-years for ulcerations and a prevalence of 54.57 cases/1000 persons for active ulcerations, highlighting significant geographic and methodological variations in DF disease rates.
Key findings
- Pooled incidence rates were 10.93 cases/1000 person-years for ulcerations and 3.58 for amputations.
- Pooled prevalence estimates included 54.57 cases/1000 persons for active ulcerations and 14.75 for amputations.
- Substantial heterogeneity (I² > 90%) was observed, influenced by geographic region and study methodology.
- Rates in America and Africa were generally above the global pooled average.
Why it matters
Understanding the global incidence and prevalence of diabetic foot disease is crucial for public health planning and resource allocation. The significant variations across regions and methodologies can inform targeted interventions and improve patient outcomes in diabetes care.