Levocetirizine-induced paradoxical fixed drug eruption: A case report with causality assessment.

Indian J PharmacolSep 2, 2026 (epub)
Case ReportDermatologyAllergy & Immunology

Ambili Remesh, Madhavi S Lekshmi, Subramaniam Reshmi

✦ AI-curated · Sources linked

Case in brief

A patient developed a fixed drug eruption (FDE) after self-medicating with levocetirizine, presenting with hyperpigmented patches that progressed to blisters. The causality assessment classified the reaction as probable and preventable. The patient's condition improved upon discontinuation of the drug, highlighting the need for awareness regarding potential adverse reactions to commonly used antihistamines.

Diagnostic / clinical pearl

Clinicians should be aware that levocetirizine, despite its safety profile, can induce fixed drug eruptions in susceptible individuals.

Why it matters

This case underscores the importance of pharmacovigilance and patient education to prevent adverse drug reactions associated with self-medication.

Source

PubMed · PMID 42683994

Published in Indian J Pharmacol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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