Frequency of Human Brucellosis Complications in West Asia: A Systematic Review and Meta-Analysis.

MicrobiologyopenSep 8, 2026
Clinical ResearchInfectious Diseases

Aliasghar Fakhri-Demeshghieh, Elnaz Rostamzaman, Fatemeh Sayareh et al.

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In 30 seconds

This systematic review and meta-analysis examined the complications of brucellosis in the West Asia/Middle East region, analyzing data from 240 studies. The highest pooled estimate for complications was musculoskeletal involvement, reported in 50% of cases (95% CI: 39%-61%). The study highlights the variability in complication reporting across different countries.

Key findings

  • Musculoskeletal involvement was the most common complication, with a pooled estimate of 50% (95% CI: 39%-61%).
  • A total of 240 studies were included in the analysis, with the majority from Turkey.
  • Complications such as eye involvement were inconsistently reported across countries.
  • There is a need for standardization in reporting brucellosis complications.

Why it matters

Understanding the frequency and types of complications associated with brucellosis is crucial for clinicians in endemic regions. This knowledge can inform diagnosis, management, and patient education regarding potential health outcomes.

Source

Published in Microbiologyopen. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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