Global prevalence of tigecycline-resistant foodborne Enterobacterales along the food chain: A meta-analysis.
Food Res IntAug 19, 2026 (epub)
Mei Li, Siyue Wang, Kaiyi Zhao et al.
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In 30 seconds
This meta-analysis evaluated the global prevalence of tigecycline-resistant Enterobacterales in food and food-producing animals, analyzing 104 studies. The overall resistance rate was found to be 4.36%, with E. coli representing 93.01% of resistant strains. The highest resistance was observed at farms (5.05%), particularly in Asia (5.30%).
Key findings
- The overall prevalence of tigecycline-resistant Enterobacterales was 4.36% (95% CI: 2.83%-6.20%).
- Among resistant strains, tet(X4) prevalence was 73.81% (95% CI: 43.79%-94.96%).
- E. coli accounted for 93.01% of the resistant strains identified.
- The highest resistance rate was found at farms (5.05%), followed by retail markets (2.61%).
Why it matters
The emergence of tigecycline-resistant Enterobacterales poses a significant public health risk, particularly as E. coli is a common pathogen. Understanding resistance patterns can inform strategies to mitigate this threat in the food supply chain.