Ventricular-arterial coupling during exercise and tilt assessed using a pulse wave velocity-to-global longitudinal strain ratio.
Skye H T Ling, Lea Nguyen, Jessica N Jasiak et al.
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In 30 seconds
This randomized controlled trial assessed ventricular-arterial coupling (VAC) using the E a /E es ratio and a novel PWV/GLS ratio in 20 healthy young adults during exercise and head-up tilt. The study found that E a /E es declined with increasing exercise intensity, while PWV/GLS was responsive to tilt but less sensitive to exercise intensity, indicating different behaviors of these metrics under varying physiological conditions.
Key findings
- E a /E es declined with increasing exercise intensity (P < 0.01).
- E a /E es showed no differences between supine and head-up tilt (P > 0.05).
- PWV/GLS differed from supine to head-up tilt at rest (P < 0.01).
- PWV/GLS was less sensitive to exercise intensity, with differences only from baseline (P < 0.05).
Why it matters
Understanding the dynamics of ventricular-arterial coupling is crucial for evaluating cardiovascular function under stress. This study highlights the potential of PWV/GLS as a complementary measure to E a /E es, which may enhance the assessment of cardiac performance in varying physiological states.