Malignant pertussis in a young infant.
Sumayah Bachal
✦ AI-curated · Sources linked
Case in brief
A young infant presented with malignant pertussis, characterized by extreme leucocytosis and respiratory failure, alongside additional bloodstream infections during hospitalization. The case highlights the importance of early recognition and aggressive supportive care. The infant's condition improved with careful monitoring and management, including the successful use of hydroxyurea to address hyperleucocytosis.
What made this case unusual
The successful use of hydroxyurea to manage extreme hyperleucocytosis without resorting to exchange transfusion or leucapheresis is a notable aspect of this case.
Diagnostic / clinical pearl
Clinicians should be aware that malignant pertussis can lead to severe complications in infants, necessitating prompt recognition and intervention.
Why it matters
This case underscores the importance of maternal immunization as a preventive measure against pertussis in newborns, particularly in regions with high infant populations.