Effect of intradialytic exercise on cardiovascular structural and functional parameters in maintenance haemodialysis: a systematic review and meta-analysis.
Zhi Xiao, Chao Fu, Weiwei Li
✦ AI-curated · Sources linked
In 30 seconds
This systematic review and meta-analysis evaluated the effects of intradialytic exercise (IDE) on cardiovascular parameters in patients undergoing maintenance haemodialysis (MHD). Fourteen studies with 934 participants were analyzed, revealing that IDE significantly increased left ventricular end-diastolic volume by 14.15 mL and improved left ventricular ejection fraction by 2.21%. Additionally, it reduced pulse wave velocity and diastolic blood pressure, while effects on left ventricular mass index and systolic blood pressure were not significant.
Key findings
- IDE increased left ventricular end-diastolic volume by 14.15 mL.
- Left ventricular ejection fraction improved by 2.21%.
- Pulse wave velocity decreased by 1.36 m/s.
- Diastolic blood pressure was reduced by 4.54 mm Hg.
Why it matters
Improving cardiovascular health in patients on maintenance haemodialysis is crucial, as they are at high risk for cardiovascular events. This study suggests that intradialytic exercise may enhance cardiac function and reduce arterial stiffness, potentially leading to better patient outcomes.
What to keep in mind
The study identified concerns regarding risk of bias and substantial heterogeneity for some outcomes, which may affect the reliability of the findings.