Traditional, complementary, and integrative medicine therapies for mild/moderate acute COVID-19: a systematic review and network meta-analysis.
PhytomedicineAug 27, 2026 (epub)
Anqi Li, Jun Ren, Gordon H Guyatt et al.
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In 30 seconds
This systematic review and network meta-analysis evaluated the effectiveness of Traditional, Complementary, and Integrative Medicine (TCIM) therapies for mild/moderate acute COVID-19 in 18,627 patients across 69 trials. The study found that Lianhua Qingwen, Kovir capsule, and honey with Nigella sativa likely reduced symptom resolution time by 2.82 days, 3.14 days, and 3.00 days, respectively, compared to standard care.
Key findings
- Lianhua Qingwen reduced time to symptom resolution by 2.82 days compared to standard care.
- Kovir capsule reduced symptom duration by 3.14 days, showing moderate certainty evidence.
- Honey and Nigella sativa likely reduced symptom duration by 3.00 days.
- Andrographis paniculata extract probably decreased hospital admissions by 15 per 1000 patients at moderate risk.
Why it matters
Understanding the effectiveness of TCIM therapies can guide clinicians in managing mild to moderate COVID-19 cases, potentially improving patient outcomes and symptom management.