Clinical Perspective on Exophiala dermatitidis, A Systematic Review of Cases Reported Globally over 36 Years.
MycopathologiaSep 16, 2026 (epub)
Tianyang Chen, Mingyuan Han, Ying Miao et al.
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In 30 seconds
This systematic review analyzed 77 reported cases of Exophiala dermatitidis infections from 1989 to 2024, highlighting a rise in cases, particularly since 2010. The study found that 54.55% of infections occurred in immunocompromised individuals, with deep-seated infections being most prevalent (76.62%). The mortality rate was notably high for central nervous system infections (63.63%).
Key findings
- 64.9% of cases were reported since 2010, indicating increased awareness.
- 54.55% of infections occurred in immunocompromised hosts.
- 76.62% of infections were deep-seated.
- 63.63% mortality rate for central nervous system infections.
Why it matters
Understanding the epidemiology and risk factors associated with Exophiala dermatitidis is crucial for clinicians, as it highlights the need for vigilance in diagnosing and managing infections, particularly in immunocompromised patients.