Biofilm-producing Acinetobacter baumannii in Asia: mapping the clinical burden and antimicrobial resistance through systematic review and meta-analysis.
BiofoulingSep 16, 2026 (epub)
Indu Singh, Anil Kumar, Indira Kumari Verma et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the prevalence of biofilm-forming Acinetobacter baumannii in clinical isolates across Asia. The study found a pooled prevalence of 67% (95% CI = 58.50, 75.31) for biofilm-forming strains, with significant heterogeneity (I² = 98.8%). Notably, China reported the highest prevalence at 99.04% (95% CI = 97.2, 100.9).
Key findings
- The pooled prevalence of biofilm-forming A. baumannii in Asia was 67% (95% CI = 58.50, 75.31).
- Strong biofilm-forming A. baumannii prevalence was 20.37% (95% CI = 19.31, 21.43).
- Moderate biofilm-forming A. baumannii prevalence was 30.28% (95% CI = 29.17, 31.40).
- The ompA gene was prevalent in 65.38% of biofilm-forming A. baumannii isolates.
Why it matters
The high prevalence of biofilm-forming A. baumannii in healthcare settings poses significant challenges for infection control and treatment, highlighting the need for enhanced screening and preventive strategies to combat multidrug resistance.