Recurrent Plasmodium falciparum Malaria after Delayed Hemolysis Induced by Artemether-Lumefantrine.

Am J Trop Med HygSep 17, 2026 (epub)
Case ReportInfectious DiseasesHematologyOpen access

Kosuke Asano, Tokio Hoshina, Tomomi Miyamoto et al.

✦ AI-curated · Sources linked

Case in brief

A previously healthy 39-year-old Japanese man developed Plasmodium falciparum malaria after travel to Togo and received artemether-lumefantrine in the Philippines. Persistent fever and fatigue led to hospital assessment, where delayed hemolysis attributed to treatment was diagnosed. He improved with supportive care, including transfusion, but was later readmitted with malaria recrudescence and hemolytic anemia. Atovaquone-proguanil treatment was followed by clinical improvement.

What made this case unusual

Delayed hemolysis after artemether-lumefantrine was followed by recrudescent P. falciparum malaria with hemolytic anemia, linking two post-treatment complications in one patient.

Diagnostic / clinical pearl

Persistent or recurrent symptoms after artemether-lumefantrine warrant assessment for both delayed hemolysis and recrudescent malaria.

Why it matters

The authors suggest considering careful follow-up for at least 4 weeks after artemether-lumefantrine treatment.

Source

PubMed · PMID 42753717Free full text on PubMed Central

Published in Am J Trop Med Hyg. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

ShareTelegramLinkedIn

AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

More in Infectious Diseases

Clinical ResearchPreventive Medicine / Public Health

2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.

This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.

Nutr RevNov 12, 2026Read summary
Clinical ResearchOrthopedic Surgery

Prevention of Venous Thromboembolism after Total Hip or Knee Replacement.

This multicenter randomized comparative-effectiveness noninferiority trial compared 30 days of aspirin, warfarin, or rivaroxaban for VTE prophylaxis after elective total hip or knee arthroplasty.

N Engl J MedNov 12, 2026Read summary
Clinical ResearchAnesthesiology

Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.

This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…

BMJNov 11, 2026Read summary

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text
Create my personalized digestSee plans

Prefer listening? Personalized audio digests are available with Pro.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.