Rare ophthalmic complication of tuberculosis meningitis: tuberculosis orbital apex syndrome.

BMJ Case RepSep 22, 2026 (epub)
Case ReportOphthalmologyInfectious DiseasesPathology (Anatomic & Clinical)

Wilson X Wang, Mary-Grace R Reeves, Katherine E Schwetye et al.

✦ AI-curated · Sources linked

Case in brief

A woman in her mid-60s presented with orbital apex syndrome, characterized by dysfunction of multiple cranial nerves. Diagnostic challenges arose due to the rarity of tuberculosis-related OAS in non-endemic regions. A dural biopsy confirmed tuberculosis meningitis with necrotising granulomas and acid-fast bacilli. Following 2 months of modified anti-tuberculosis therapy, she showed improvement in extraocular motility and visual acuity.

Diagnostic / clinical pearl

Clinicians should consider tuberculosis as a potential cause of orbital apex syndrome, especially in atypical presentations in non-endemic areas.

Source

PubMed · PMID 42772932

Published in BMJ Case Rep. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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