Systematic Review on the Safety of Physical Exercise in Hypertrophic Cardiomyopathy: Recommendations from the Brazilian Society of Cardiology.
Arq Bras CardiolSep 21, 2026 (epub)
Clinical ResearchCardiology
Ricardo Stein, Rodrigo Otávio Bougleux Alô, Luiz Eduardo Fonteles Ritt et al.
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In 30 seconds
This systematic review evaluated the safety of physical exercise (PE) in adults with hypertrophic cardiomyopathy (HCM) by analyzing eight studies, including 9,744 participants. The findings indicated no increased risk of mortality or severe arrhythmic events associated with PE, even at moderate or vigorous intensities. The review supports encouraging PE based on individualized assessments.
Key findings
- No studies reported increased mortality or severe arrhythmic events linked to PE in HCM patients.
- A Korean study showed reduced all-cause mortality with higher physical activity intensity.
- Syncope was reported as a rare occurrence among participants engaging in PE.
- Competitive sports in low-risk athletes were not associated with severe adverse events.
Why it matters
Understanding the safety of physical exercise in HCM patients is crucial for clinicians, as it can help guide recommendations and improve patient quality of life while managing risks associated with the condition.