PCR-Confirmed Convexity Subarachnoid Neurocysticercosis with Negative Serology: A Case Report.
Aristos Aristodimou, Zacharias Raptopoulos, Jan Richter et al.
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Case in brief
A patient with a six-month history of focal seizures was diagnosed with convexity subarachnoid neurocysticercosis after surgical excision of a cystic lesion. Definitive diagnosis was confirmed through PCR detection of Taenia solium DNA in the excised tissue. Following 14 days of dual antiparasitic therapy, the patient remained free of neurological symptoms during a 12-month follow-up.
Diagnostic / clinical pearl
This case illustrates the limitations of conventional imaging in diagnosing neurocysticercosis and emphasizes the importance of molecular techniques like PCR for definitive diagnosis.
Why it matters
The case highlights the diagnostic challenges faced by clinicians in non-endemic regions and the need for a structured approach to infectious diseases.