Lymphocutaneous sporotrichosis: A case report from southeastern China and review of the literature.
Xiaoqing Wang, Jing Bian, Jianping Xu et al.
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Case in brief
A 53-year-old male presented with multiple ulcerated lesions, leading to a diagnosis of lymphocutaneous sporotrichosis. Pathological analysis showed an inflammatory reaction, while imaging studies were normal. Definitive diagnosis was achieved through fungal culture and metagenomic next-generation sequencing (mNGS) of wound pus. The patient was treated with oral itraconazole and showed complete recovery without recurrence during follow-up.
What made this case unusual
The rapid diagnosis of sporotrichosis using metagenomic next-generation sequencing (mNGS) highlights its potential as a valuable diagnostic tool in cases where traditional methods may be slower.
Diagnostic / clinical pearl
Metagenomic next-generation sequencing (mNGS) can facilitate the rapid identification of sporotrichosis, improving diagnostic efficiency and patient outcomes.
Why it matters
This case underscores the importance of adopting advanced molecular techniques like mNGS in clinical practice to enhance the diagnosis of fungal infections.