Meta-analysis of Asymptomatic Monkeypox Virus Prevalence in Nonendemic Regions, 2022-2024.
Kelsey J MacCuish, Robert Snyder, Kelly A Johnson et al.
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In 30 seconds
This meta-analysis examined the prevalence of asymptomatic monkeypox virus (MPXV) detections in nonendemic regions from May 2022 to September 2024. The study found a pooled prevalence of 1.0% (95% prediction interval 0.1%-11.2%) across various geographic regions and study designs, indicating a low but notable presence of asymptomatic cases.
Key findings
- The pooled prevalence of asymptomatic MPXV detections was 1.0%.
- The 95% prediction interval for prevalence ranged from 0.1% to 11.2%.
- Prevalence did not significantly differ by geographic region or study design.
Why it matters
Understanding the prevalence of asymptomatic monkeypox cases is crucial for public health strategies, as it may influence monitoring and response efforts in nonendemic regions where the virus is emerging.