Open versus closed suctioning on lung volume and oxygenation in ARDS patients with PEEP 5-10 cmH2O: A randomized controlled trial.
PLoS OneSep 30, 2026 (epub)
Clinical ResearchPulmonology
Haotian Gao, Yidie Ying, Jun Yang
✦ AI-curated · Sources linked
In 30 seconds
This randomized controlled trial compared open suctioning (OS) and closed suctioning (CS) in 60 ARDS patients on mechanical ventilation with PEEP 5-10 cmH2O. CS significantly reduced lung volume loss at 1 and 10 minutes post-suctioning compared to OS, but lung volume recovery was slower in the CS group. Notably, SpO2 was lower in the OS group at 1 minute post-suctioning.
Key findings
- CS group had significantly lower global ΔEELI at 1 minute (-0.54 ± 0.18 vs. -2.32 ± 1.34, P < .001).
- Lung volume recovery was faster in the OS group, returning to baseline by 20 minutes.
- SpO2 was significantly lower in the OS group at 1 minute (98.07 ± 1.26% vs. 99.03 ± 0.93%, P = .007).
- No significant differences in extubation and survival rates between the two groups.
Why it matters
Understanding the effects of suctioning methods on lung volume and oxygenation is crucial for optimizing care in ARDS patients. This study highlights the trade-offs between suctioning techniques, which may influence clinical decision-making in mechanical ventilation management.