Maternal and fetal outcomes of spinal tuberculosis in pregnancy: A systematic review and descriptive pooled analysis.
Anil Regmi, Abdus Sami, Surakshya Baral et al.
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From the abstract
Spinal tuberculosis (TB) in pregnancy is rare and poses diagnostic, neurological, and obstetric challenges. Data are limited to isolated case reports and small series, precluding evidence-based guidance on management and outcomes.
Reported results
Twenty-three case reports and small case series (no controls) encompassing 36 pregnancies were included. All patients received standard Anti Tubercular Therapy (ATT); 26 (72%) underwent surgery, mostly postpartum. Pooled live birth proportion was 0.77 (95% CI: 0.63-0.88). Full maternal neurological recovery was achieved in 0.85 (95% CI: 0.74-0.94).
Authors' conclusions
In published cases, timely ATT and selective surgical intervention were associated with high reported rates of live birth and maternal neurological recovery; however, these findings likely reflect selected best-case scenarios and require confirmation in prospective registries.