Efficacy and Safety of Traditional Chinese Medicine in Treating Chronic Obstructive Pulmonary Disease with Osteoporosis: A Systematic Review and Meta-Analysis.
Xulun Li, Haiqiang Wang, Huiqing Zhang et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the efficacy and safety of traditional Chinese medicine (TCM) as an adjunct to conventional treatment for chronic obstructive pulmonary disease (COPD) with osteoporosis (OP). Involving 944 patients across 11 studies, results showed that TCM combined with conventional therapy improved bone mineral density (BMD) by a standardized mean difference of 0.71 and forced expiratory volume in 1 second (FEV1) by 0.54 compared to conventional therapy alone.
Key findings
- TCM plus conventional therapy improved bone mineral density (BMD) with a standardized mean difference of 0.71.
- Forced expiratory volume in 1 second (FEV1) increased by a standardized mean difference of 0.54 with TCM.
- The TLKRBS approach had a 98.82% probability of being the best for increasing BMD.
- Adverse events were inadequately reported, limiting safety assessments.
Why it matters
The findings suggest that integrating traditional Chinese medicine with conventional treatments may enhance outcomes for patients with COPD and osteoporosis, potentially guiding clinical practice in managing these comorbid conditions.
What to keep in mind
The evidence is limited by small sample sizes, high heterogeneity, and risks of bias in the included studies.