Complexity of coronary artery disease in infarct-related cardiogenic shock and multivessel disease: a substudy of the DanGer Shock trial.
EuroInterventionOct 5, 2026 (epub)
Jasmine M Marquard, Rasmus P Beske, Christian Hassager et al.
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In 30 seconds
This study, a secondary analysis of the DanGer Shock trial, evaluated the prognostic significance of baseline and residual SYNTAX scores in 256 patients with multivessel disease and infarct-related cardiogenic shock. It found that a high baseline SYNTAX score was linked to increased odds of 180-day all-cause mortality (adjusted OR 3.12).
Key findings
- A high baseline SYNTAX score was associated with higher odds of 180-day all-cause mortality (adjusted OR 3.12).
- The residual SYNTAX score independently predicted 180-day all-cause mortality.
- In patients with isolated LM lesions, mAFP use was linked to lower odds of 180-day mortality (adjusted OR 0.17).
Why it matters
Understanding the relationship between SYNTAX scores and mortality can help clinicians assess risk in patients with multivessel disease and cardiogenic shock, potentially guiding treatment decisions.