Isolated Prostatic Tuberculosis Coexisting with Benign Prostatic Hyperplasia: A Case Report.
Mohammad Hussain Modabber, Mohammad Ibrahim Kamal, Mohammad Fahim Sarwary et al.
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Case in brief
A 70-year-old man presented with one month of lower urinary tract symptoms and recurrent urinary retention requiring repeated catheterization. His prostate-specific antigen was 5.5 ng/mL, and ultrasonography showed a 59-gr enlarged prostate consistent with benign prostatic hyperplasia (BPH). After transurethral resection, histopathology showed caseating granulomatous inflammation strongly suggestive of prostatic tuberculosis alongside BPH, with no evidence of malignancy. Primary microbiological or molecular confirmation was absent. Anti-tuberculosis treatment was started, and he had significant clinical improvement during follow-up.
What made this case unusual
Prostatic tuberculosis was unsuspected in a patient whose urinary obstruction and imaging were consistent with BPH; it was identified in resected tissue despite the absence of primary microbiological or molecular confirmation.
Diagnostic / clinical pearl
In a patient undergoing prostate resection for presumed BPH, histopathological examination can reveal coexisting prostatic tuberculosis when symptoms and imaging are nonspecific.