Fatal Rickettsia parkeri Rickettsiosis in Immunocompromised Pediatric Patient, Georgia, USA, 2025.

Emerg Infect DisOct 24, 2026
Case ReportInfectious DiseasesPediatricsOncology (Medical)HematologyPathology (Anatomic & Clinical)

Stephanie Bellman, Thomas G Fox, Sunil S Raikar et al.

✦ AI-curated · Sources linked

Case in brief

A 3-year-old boy in Georgia, USA, receiving chemotherapy for B-cell acute lymphoblastic leukemia was hospitalized with febrile neutropenia. Plasma microbial cell-free DNA sequencing confirmed Rickettsia parkeri rickettsiosis. The infection was fatal.

What made this case unusual

The case involved fatal R. parkeri rickettsiosis in a young child receiving chemotherapy for leukemia.

Diagnostic / clinical pearl

In an immunocompromised patient with febrile neutropenia, tickborne disease should remain in the differential diagnosis in relevant settings; plasma microbial cell-free DNA sequencing can confirm R. parkeri infection.

Source

PubMed · PMID 42912437

Published in Emerg Infect Dis. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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